Thee DocKtor has noticed inconsistencies of scaling, orientation, attachment, etc. that vary with graphics adaptor driver versions, Windows versions, and various monitor’s manufacturers, resolutions, and sizes. Some users describe it as “fuzzy” graphics.
To date these have been due to multiple monitors whether through a USB DisplayLink, DisplayPort Alternate Mode dock, or Thunderbolt dock, dongle, or directly attached to the local graphics adaptor.
For possible fixes to the issue of “fuzzy” display monitor renderings check out:
A great article on display monitor scaling is at:
To understand what version of Windows 10 you have, see the wiki at:
With Targus Truly Universal Docking Stations based on the DisplayLink Technology for USB display monitors in Windows 7 always enable AERO Glass.
If you are certain that the issue is with the dock, please post here and/or contact Targus to diagnose.