Thee DocKtor has noticed inconsistencies of scaling, orientation, attachment, etc. that vary with graphics adaptor driver versions, Windows versions, and various monitor’s manufacturers, resolutions, and sizes. To date these have been due to multiple monitors whether through a USB3.0 DisplayLink or DisplayPort Alternate Mode dock, dongle, or directly attached to the local graphics adaptor.
A great article on Display (The DocKtor prefers “Monitor”) scaling is at:
If you are pretty certain that the issue is with the dock, please post here and/or contact Targus to diagnose.